Research Task

Production of bioactive compounds by filamentous fungi
Design of biosynthetic pathways for bioactive compounds using machine learning technologies
Elucidation and application of gene regulatory system by amino acid tandem repeats
Research Keywords
Filamentous fungi, Secondary metabolic pathway, Tandem repeat sequence, Ribosomally synthesized and post-translationally modified peptide
Application Fields
Biomanufacturing, Biofunctional applications
Bioinformatics, Genetic engineering, Live imaging

We are working on detecting unknown biological pathways and functions by bioinformatics analyses and experimental validation. Using this approach, we have discovered a novel pathway for ribosomally synthesized and post-translationally modified peptides in filamentous fungi and a novel gene regulatory function by amino acid tandem repeats. Using these achievements, we aim to construct host strains for bioactive compound production with high yielding and wide adaptability.