Plants produce a wide variety of secondary metabolites that it is estimated over 200,000 species. On the other hand, their accumulation in the plant body is low and their supply is dependent on extraction from native plants. Therefore, there is a concern that their supply may become unstable in the future due to excessive harvesting or decrease in growing areas caused by climate change. In our laboratory, we are elucidating biosynthetic genes for useful secondary metabolites using metabolite and transcriptome analysis of various plants, and conducting a research and development to establish an alternative production platform by  heterologous protein expression systems.