【第31回ERATO共生進化機構国際セミナー】
講師：Dr. Saskia Hogenhout (John Innes Centre, UK)
演題：Unveiling the Influence of Phytoplasmas: Insights into Extended Phenotypes and Biotechnological Implications
日時：2024年4月24日（水）16:00(JST)～, Online Zoom Meeting

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Abstract: Parasites possess remarkable abilities to influence host development and behaviour, crucial for their survival and dissemination. This manipulation, especially evident in obligate parasites, showcases extended phenotypes, where an organism’s genetic impact extends beyond itself, affecting others in the ecosystem. The Hogenhout lab focuses on phytoplasmas, obligate bacterial parasites relying on insect vectors for transmission. Phytoplasmas not only alter their immediate hosts but also have far-reaching effects. They induce significant plant developmental changes, like witches’ brooms and phyllody, facilitated by effector proteins targeting critical plant transcription factors, disrupting growth pathways. Our research finds that symptomatic plants are more attractive to insect vectors, although specific symptoms aren’t always necessary. These effectors occur in diverse phytoplasmas, including those affecting economically vital crops, underscoring their pathogenic significance. We identify susceptibility factors crucial for symptom induction, offering avenues to bolster resistance in agricultural systems. Additionally, phytoplasma effector mechanisms reveal novel strategies for targeted protein degradation, with broader implications for biotechnological applications. Our findings illuminate the intricate relationships among phytoplasmas, plants, and insect vectors, providing insights into the long reach of single parasite genes in extended phenotypes. Moreover, they promise effective management of economically significant pathogens and advancements in biotechnology.

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問い合わせ先：M-ERATO-International-Seminar-ml@aist.go.jp
主催：ERATO深津共生進化機構プロジェクト https://www.jst.go.jp/erato/fukatsu/
連絡先：深津武馬（生物プロセス研究部門首席研究員, t-fukatsu@aist.go.jp)